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Figure 2 | Respiratory Research

Figure 2

From: Cigarette smoke-induced pulmonary emphysema in scid-mice. Is the acquired immune system required?

Figure 2

T- and B-cell populations in the lungs upon air or cigarette smoke exposure. Effect of cigarette smoke (CS) exposure for 6 months on T-cell populations in the lungs (absolute numbers in the lungs; determined by flow cytometry) in wild type mice and scid mice (air-exposed mice: open squares, CS-exposed mice: closed squares): (A) lung CD4+ T-lymphocytes, (B) lung CD8+ T-lymphocytes, (C) activated lung CD4+ T-lymphocytes, (D) activated lung CD8+ T-lymphocytes and (E) lung B-lymphocytes. Animals (n = 8) were exposed to 5 cigarettes/group/exposure; 4 exposures/day; 5 days/week (* p < 0.05 and ** p < 0.001 versus air-exposed mice).

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