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Table 4 Frequencies of immunoglobulin isotypes below the lower limits of normal.

From: Pathophysiological classification of chronic rhinosinusitis

 

Nasal Polyps with Aspirin Sensitivity (NPasa)

Nasal Polyps with Other Features (NPother)

CRS without (s) Nasal Polyps (CRSsNP)

Osteomeatal Complex Disease (OMC)

IgE<10 IU/ml

4/14 (29%)

4/24 (17%)

11/25 (44%) {0.03}

9/20 (45%) {0.03}

IgA

2/12 (17%)

2/21 (10%)

5/18 (28%)

2/14 (14%)

IgM

1/12 (8%)

3/21 (14%)

7/18 (39%)

3/14 (21%)

IgG1

4/12 (33%)

5/21 (24%)

8/18 (44%)

5/14 (36%)

IgG2

2/12 (17%)

2/21 (10%)

4/18 (22%)

2/14 (14%)

IgG3

3/12 (25%)

3/21 (14%)

8/18 (44%)

3/14 (21%)

IgG4

1/12 (8%)

3/21 (14%)

5/18 (28%)

3/14 (21%)

IgE+IgG1/3 * A

2/12 (17%)

1/19 (5%)

8/18 (44%) {0.007}

2/14 (14%)

  1. * IgE <10 IU/ml plus either low IgG1 or IgG3. ANOVA: A = 0.02. {p} = Fisher's Exact test vs. NPother.