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Table 2 Flow and pressure values obtained in response to 100% intensity PNS applied during expiration and inspiration in normals and OSA subjects. *: significant difference between inspiratory and expiratory values in a given group. Mean ± SEM.

From: Impediment in upper airway stabilizing forces assessed by phrenic nerve stimulation in sleep apnea patients

 

Expiratory

Inspiratory

 

Normal Subjects

OSA Subjects

Normal Subjects

OSA Subjects

Imax (ml.s-1)

716 ± 36

739 ± 51

990 ± 42 *

1038 ± 58 *

Peso peak at 100% stimulation I (cm H2O)

-17.6 ± 1.8

-14.0 ± 2.0

-21.1 ± 1.0 *

-17.7 ± 1.9 *

Pphar peak at 100% stimulation I (cm H2O)

-11.2 ± 2.2

-11.1 ± 2.1

-15.9 ± 1.5 *

-14.7 ± 1.4 *

R Phar 400 ml/s (cm H2O.ml-1.s)

9.0 ± 0.7

9.5 ± 0.9

10.5 ± 1.3

8.5 ± 0.9

R Phar Imax (cm H2O.ml-1.s)

9.2 ± 0.8

11.1 ± 1.3

10.2 ± 0.9

8.4 ± 0.7

Imax lim (ml.s-1)

742 ± 248

752 ± 352

981 ± 297 *

1014 ± 348 *

Pphar lim (cm H2O)

-8.4 ± 4.2

-7.2 ± 3.3

-12.5 ± 4.1 *

-9.6 ± 3.6 *

Δ I (ml.s-1)

234 ± 26

256 ± 37

258 ± 35

234 ± 24

% twitches with FL

76.6 ± 3.4

79.0 ± 4.4

75.0 ± 3.5

84.4 ± 4.1