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Figure 1 | Respiratory Research

Figure 1

From: Passive immunoprophylaxis and therapy with humanized monoclonal antibody specific for influenza A H5 hemagglutinin in mice

Figure 1

Humanization of mouse mAbs VN04-2 and VN04-3. A, Diagrammatic representation of the expression vector used to create chimeric antibodies; CL and CH refer to the constant regions of the human Kappa light and human IgG1, respectively; L refers to the leader sequence. B, ELISA to show presence of human constant regions, antibodies bound to immunosorbent plates were detected using secondary antibodies specific for human IgG and mouse IgG. Following addition of TMB substrate absorbance was measured at 450 nm.

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Respiratory Research

ISSN: 1465-993X

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