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Figure 5 | Respiratory Research

Figure 5

From: Azithromycin reduces spontaneous and induced inflammation in ΔF508 cystic fibrosis mice

Figure 5

Time course of cytokine release in bronchoalveolar lavage fluid obtained 3 h, 24 h and 48 h after intratracheal instillation of P aeruginosa LPS from CF and wild-type (WT) mice. (A) macrophage inflammatory protein-2 (MIP-2); (B) tumor necrosis factor-alpha (TNF-α); (C) interleukin (IL)-10. Values, expressed as pg/ml, are means ± SEM for 6–9 animals per each of the 8 subgroups from the same experiment as that used to generate Figure 4. *p < 0.05; †p < 0.001; ‡p < 0.0005 for comparison of corresponding mean value vs. that obtained at the same time point in the wild-type group of mice.

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