Heartburn | Regurgitation | Heartburn and regurgitation | |||||||
---|---|---|---|---|---|---|---|---|---|
Challenge agent | Age | n | % with AHR | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p |
Methacholine* | 9 | 716 | 16.9 | 1.40 (0.81, 2.43) | 0.234 | 1.22 (0.55, 2.73) | 0.623 | 1.51 (0.63, 3.61) | 0.354 |
11 | 677 | 10.8 | 1.62 (0.84, 3.11) | 0.150 | 1.89 (0.80, 4.48) | 0.147 | 3.00 (1.22, 7.40) | 0.017 | |
13 | 637 | 8.3 | 1.63 (0.76, 3.51) | 0.210 | 1.78 (0.66, 4.82) | 0.253 | 2.92 (1.04, 8.17) | 0.041 | |
15 | 743 | 8.3 | 1.92 (1.00, 3.70) | 0.051 | 2.94 (1.35, 6.42) | 0.007 | 3.86 (1.66, 8.97) | 0.002 | |
21 | 795 | 7.7 | 2.59 (1.38, 4.85) | 0.003 | 4.61 (2.26, 9.40) | <0.001 | 5.56 (2.53, 12.2) | <0.001 | |
Salbutamol | 18 | 758 | 7.8 | 1.01 (0.46, 2.21) | 0.978 | 1.13 (0.39, 3.29) | 0.818 | 1.14 (0.34, 3.85) | 0.836 |