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Figure 4 | Respiratory Research

Figure 4

From: Prolonged ozone exposure in an allergic airway disease model: Adaptation of airway responsiveness and airway remodeling

Figure 4

(A) Bronchioles exposed to filtered air have normal-appearing bronchioles and bronchiolo-alveolar portal and a normal transition from the low columnar epithelium lining the terminal bronchioles to the attenuated epithelium lining the alveoli. (B–D) Bronchioles exposed to 2 ppm ozone for 4, 8, and 12 weeks. (B) Pseudostratified bronchiolar epithelium and goblet cell metaplasia. (C)Markedly increased number of goblet cells. (D) Peribronchiolar collagen deposition and thickened smooth muscle cell coat. Original magnification, ×200. Scale bar = 100 μm.

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Respiratory Research

ISSN: 1465-993X

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