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Figure 7 | Respiratory Research

Figure 7

From: Lung development in laminin γ2 deficiency: abnormal tracheal hemidesmosomes with normal branching morphogenesis and epithelial differentiation

Figure 7

Hemidesmosomal proteins. Sections from P1-2 littermate control and Lamc2-/- skin and tracheas were stained with antibodies against BP180 and integrin β4 to examine the distribution of hemidesmosomal proteins. In the skin (a-b), staining with BP180 antibody showed a continuous pattern in the littermate control mouse, whereas a discontinuous pattern was seen with the Lamc2-/- (b) mouse. In the trachea (c-d), BP180 staining was similar in littermate control (c) and Lamc2-/- (d) mice. Immunofluorescence with antibody against integrin β4 also did not reveal a difference in littermate control (e) and Lamc2-/- (f) tracheas. Original magnification 200×.

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