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Figure 3 | Respiratory Research

Figure 3

From: Endotoxin induced peritonitis elicits monocyte immigration into the lung: implications on alveolar space inflammatory responsiveness

Figure 3

Alveolar macrophage expansion elicited in endotoxin-induced peritonitis is CCR2-dependent. Wild-type mice or CCR2-deficient mice were either left untreated or received a single intraperitoneal LPS application (50 μg/mouse) or wild-type mice were pretreated with function-blocking anti-CD18 antibodies prior to and every 24 h post intraperitoneal LPS application, as indicated. At 96 h post-treatment, mice were sacrificed and alveolar macrophages (black bars) and neutrophils (white bars) contained in bronchoalveolar lavage were quantified. Values are given as mean ± SEM of five mice per treatment group. * indicates p < 0.01 compared to all other treatment groups.

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