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Figure 6 | Respiratory Research

Figure 6

From: Airway smooth muscle relaxation results from a reduction in the frequency of Ca2+ oscillations induced by a cAMP-mediated inhibition of the IP3 receptor

Figure 6

Relationship between the reduction in Ca2+oscillation frequency in SMCs and airway relaxation. The relaxation state (percentage of the MCh-induced contraction) and corresponding Ca2+ oscillation frequency (ratio to the frequency of MCh-induced Ca2+ oscillations) upon exposure to ISO, FSK and 8-bromo-cAMP (at various concentrations) were plotted and fitted with a logistic function. The data indicates that a greater airway relaxation correlated with a larger reduction in the Ca2+ oscillation frequency.

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