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Figure 5 | Respiratory Research

Figure 5

From: Hypoxic vasoconstriction of partial muscular intra-acinar pulmonary arteries in murine precision cut lung slices

Figure 5

HPV of intra-acinar arteries requires ROS and flavoproteins. Videomorphometric analysis of HPV was performed in absence or presence of the ROS scavenger NBT (A) and of the flavoprotein inhibitor DPI (B), respectively. In both cases, HPV was inhibited whereas U46619-induced vasoconstriction was unaffected. The changes in the luminal areas of the vessels are given as relative values, setting the luminal area immediately before exposure to hypoxia as 100%. Data are presented as means ± SEM. *p = 0.05, ** p = 0.01, n.s. = not significant.

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Respiratory Research

ISSN: 1465-993X

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