Figure 4From: Migratory marker expression in fibroblast foci of idiopathic pulmonary fibrosisLAM5γ2 expression in control samples. LAM5γ2 expression is observed in a subset of regenerating epithelial cells in cryptogenic organising pneumonia (COP, a), and diffuse alveolar damage/acute interstitial pneumonia (AIP/DAD, b), but is completely absent in allergic extrinsic alveolitis (AEA, c) and desquamative interstitial pneumonia (DIP, d), used as controls. In this UIP-like case (systemic sclerosis LAM5γ2 immunoreactivity was restricted to pneumocytes overlying FF (e, arrow), but the "sandwich" pattern was not observed despite the high number of fibroblast foci, as shown by tenascin immunostaining on serial sections (f, arrows).Back to article page