From: Gender and respiratory factors associated with dyspnea in chronic obstructive pulmonary disease
Clinical & Physiological Characteristics | Men* n = 50 | Women* n = 50 | p value |
---|---|---|---|
Age (years old) | 67 ± 8 | 56 ± 11 | <0.001 |
Pack years history | 69 ± 27 | 48 ± 28 | <0.001 |
MMRC (points) | Â | Â | Â |
0 (%) | 35 (70) | 11 (22) | <0.001 |
1–4 (%) | 15 (30) | 35 (78) | <0.001 |
BMI (kg/m 2 ) | 27 ± 4 | 27 ± 6 | ns |
BMI≤21(%) | 5 (10%) | 8 (16%) | ns |
ffmi (kg/m 2 ) | 18 ± 3 | 15 ± 2 | <0.001 |
Charlson Score (points) | 2 (2–3) | 2(1–4) | ns |
FEV 1 % of predicted | 63 ± 17 | 63 ± 17 | ns |
FVC % of predicted | 91 ± 18 | 92 ± 21 | ns |
FEV 1 /FVC % of predicted | 60 ± 12 | 60 ± 13 | ns |
FRC % of predicted | 134 ± 38 | 134 ± 27 | ns |
TLC % of predicted | 113 ± 21 | 114 ± 21 | ns |
IC/TLC (%) | 36 ± 8 | 36 ± 7 | ns |
IC/TLC<0.25 (%) | 6 (12) | 4 (7) | ns |
Respiratory rate | 18 ± 4 | 19 ± 4 | ns |
Ti/Ttot | 0,40 ± 0,06 | 0.41 ± 0.06 | ns |
PaO 2 (mmHg) | 76 ± 12 | 76 ± 9 | ns |
PaCO 2 (mmHg) | 41 ± 4 | 40 ± 4 | ns |
DLCO (%) | 87 ± 30 | 72 ± 20 | 0.02 |
P imax % of predicted | 67 ± 22 | 50 ± 20 | <0.001 |
P 0.1 | 0.27 ± 0.11 | 0.34 ± 0.19 | <0.001 |
P 0.1 % of predicted | 117 ± 12 | 155 ± 35 | <0.001 |
P 0.1 /P imax | 0.04 ± 0.02 | 0.06 ± 0.05 | <0.001 |
6MWD (meters) | 522 ± 90 | 461 ± 85 | 0.001 |
IC/TLC post 6MWD(Lt) | 0.31 ± 0.09 | 0.31 ± 0.08 | ns |
VAS pre 6MWD (cm) | 1 ± 1 | 3 ± 2 | 0.05 |
VAS post 6MWD (cm) | 3 ± 2 | 5 ± 2 | 0.005 |