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Table 1 Clinical and physiologic characteristics of men and women participating in the study.

From: Gender and respiratory factors associated with dyspnea in chronic obstructive pulmonary disease

Clinical & Physiological Characteristics

Men* n = 50

Women* n = 50

p value

Age (years old)

67 ± 8

56 ± 11

<0.001

Pack years history

69 ± 27

48 ± 28

<0.001

MMRC (points)

   

0 (%)

35 (70)

11 (22)

<0.001

1–4 (%)

15 (30)

35 (78)

<0.001

BMI (kg/m 2 )

27 ± 4

27 ± 6

ns

BMI≤21(%)

5 (10%)

8 (16%)

ns

ffmi (kg/m 2 )

18 ± 3

15 ± 2

<0.001

Charlson Score (points)

2 (2–3)

2(1–4)

ns

FEV 1 % of predicted

63 ± 17

63 ± 17

ns

FVC % of predicted

91 ± 18

92 ± 21

ns

FEV 1 /FVC % of predicted

60 ± 12

60 ± 13

ns

FRC % of predicted

134 ± 38

134 ± 27

ns

TLC % of predicted

113 ± 21

114 ± 21

ns

IC/TLC (%)

36 ± 8

36 ± 7

ns

IC/TLC<0.25 (%)

6 (12)

4 (7)

ns

Respiratory rate

18 ± 4

19 ± 4

ns

Ti/Ttot

0,40 ± 0,06

0.41 ± 0.06

ns

PaO 2 (mmHg)

76 ± 12

76 ± 9

ns

PaCO 2 (mmHg)

41 ± 4

40 ± 4

ns

DLCO (%)

87 ± 30

72 ± 20

0.02

P imax % of predicted

67 ± 22

50 ± 20

<0.001

P 0.1

0.27 ± 0.11

0.34 ± 0.19

<0.001

P 0.1 % of predicted

117 ± 12

155 ± 35

<0.001

P 0.1 /P imax

0.04 ± 0.02

0.06 ± 0.05

<0.001

6MWD (meters)

522 ± 90

461 ± 85

0.001

IC/TLC post 6MWD(Lt)

0.31 ± 0.09

0.31 ± 0.08

ns

VAS pre 6MWD (cm)

1 ± 1

3 ± 2

0.05

VAS post 6MWD (cm)

3 ± 2

5 ± 2

0.005

  1. mean ± SD or median(25th–75th percentiles) depending on scale measurement and sample distribution; ns = statistically non significant.