Figure 6

Effects of NOR-1 and PKC inhibitors on the MUC5AC mucin synthesis from the A549 cells. A549 cells were exposed to NOR-1 (0.5 mM) in the presence of ERK-inhibitor, PD98059 (40 μM) or PKC-α,β inhibitors, GÖ6976 (10 nM) or PKC-δ inhibitors, rottlerin (4 μM) or specific PKC inhibitors, Calphostin C (0.5 μM). The results were expressed as means ± SE of eight different experiments. * p < 0.05 versus control, † p < 0.05 versus NOR-1 stimulated cells.