Table 6 Association between plasma marker concentrations and % DLCO, unadjusted
Classification | Plasma marker | β†| 95% CI | p‡ |
|---|---|---|---|---|
Apoptosis | Fas | 0.01 | 0.001, 0.01 | 0.01 |
| Â | FasL | -0.0004 | -0.007, 0.006 | 0.89 |
Acute phase | CRP | -0.01 | -0.02, 0.01 | 0.33 |
| Â | MPO | -0.005 | -0.01, 0.004 | 0.30 |
Chemokines | CCL2/MCP -1 | -0.003 | -0.01, 0.0004 | 0.09 |
|  | CCL3/MIP-1α | 0.001 | -0.02, 0.02 | 0.92 |
|  | CCL4/MIP-1β | -0.02 | -0.03, -0.001 | 0.04 |
| Â | CCL5/RANTES | -0.01 | -0.02, -0.002 | 0.02 |
| Â | CCL11/eotaxin | -0.002 | -0.01, 0.002 | 0.31 |
| Â | CXCL8/IL-8 | -0.005 | -0.01, -0.002 | < 0.01 |
| Â | CXCL9/Mig | -0.01 | -0.02, -0.004 | < 0.01 |
T H Related Cytokines | IFN-γ | -0.03 | -0.04, -0.01 | < 0.001 |
| Â | IL-2 | -0.04 | -0.06, -0.02 | < 0.01 |
|  | IL-2R§ | -0.005 | -0.01, 0.002 | 0.18 |
| Â | IL-4 | -0.03 | -0.06, -0.01 | < 0.01 |
| Â | IL-13 | -0.02 | -0.03, -0.01 | < 0.001 |
Inflammation | TNF-α | -0.02 | -0.03, -0.005 | < 0.01 |
|  | TNFRI§ | 0.001 | -0.01, 0.01 | 0.79 |
|  | TNFRII§ | 0.001 | -0.004, 0.005 | 0.84 |
|  | IL-1β | -0.01 | -0.03, 0.004 | 0.13 |
| Â | IL-6 | -0.01 | -0.02, 0.004 | 0.17 |
| Â | IL-10 | -0.01 | -0.01, 0.003 | NE* |
Growth Factors | EGF | -0.01 | -0.02, 0.0001 | 0.05 |
|  | EGFR§ | 0.002 | -0.001, 0.005 | 0.12 |
|  | FGFβ | NE* | NE* | NE* |
| Â | G-CSF | -0.01 | -0.02, -0.002 | 0.02 |
| Â | HGF | -0.005 | -0.01, 0.001 | 0.08 |
| Â | VEGF | NE* | NE* | NE* |