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Figure 1 | Respiratory Research

Figure 1

From: Heme oxygenase-1 prevents smoke induced B-cell infiltrates: a role for regulatory T cells?

Figure 1

HO-1 protein expression. A: Protein bands for HO-1 (above band) and β-actin (loading control) detected by western blot analysis after long term smoke exposure and protoporphyrin treatment. Three animals per group are shown. B: A representative picture of the HO-1 expression (dark red) in lung tissue is shown for each group (25×). Particularly, alveolar macrophages (indicated with a closed arrow) show an increased HO-1 expression after CoPP treatment. The epithelium stains faintly in all groups and no differences were observed between the groups. The brown cells (indicated with an open arrow) are pigmented macrophages, a result of the smoke exposure. S: smoke, SS: Sham smoke. Mice were divided into 6 groups; 1. Phosphate buffered saline (PBS) + smoke, 2. Cobalt protoporphyrin (CoPP) + smoke, 3. Tin protoporphyrin (SnPP) + smoke, 4. PBS + sham smoke, 5. CoPP + sham smoke, 6. SnPP + sham smoke.

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