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Figure 2 | Respiratory Research

Figure 2

From: Altered prostanoid production by fibroblasts cultured from the lungs of human subjects with idiopathic pulmonary fibrosis

Figure 2

Baseline and IL-1β-stimulated 6-κ-PGF:TXB2 ratio expressed as median. IPF lung fibroblasts (HF-IPF) (n = 6) and normal human lung fibroblasts (HF-NL) (n = 5) were incubated with or without IL-1β (2.5 ng/ml) for 24 h. At this time culture media was replaced with media containing arachidonic acid (30 μM) and fibroblasts were incubated for 30 min. A significantly decreased ratio was observed at baseline in HF-IPF compared to HF-NL (P = 0.028) and a similar trend under stimulated conditions (P = 0.09).

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