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Table 1 Challenges for effective treatment and vaccination of respiratory syncytial virus

From: Potential therapeutic implications of new insights into respiratory syncytial virus disease

Aim

Prevent RSV bronchiolitis in infants under 6 months:

   Maternal of neonatal vaccination

   Passive antibody administration

Studies are required:

To identify factors that induce Th1 versus Th2 responses

To gain an understanding of tolerance and immune suppression

To gain an understanding the role of nonprotein antigens

To control IgE responses

To boost IgA responses

To make practical improvements to DNA vaccination

To develop new adjuvants

  1. RSV, respiratory syncytial virus; Th, T-helper.