Skip to main content

Table 1 Hospitalization rates

From: Immunoprophylaxis of respiratory syncytial virus: global experience

 

Children ≤ 2 years old with BPD/CLD (n = 3675)

Infants at gestational age 29–32 weeks without CLD (n = 4854)

Infants at gestational age 32–35 weeks without CLD (n = 2829)

Reference (country)

Untreated

Palivizumab

Untreated

Palivizumab

Untreated

Palivizumab

[23] (USA)

36.7% (30)

-

-

-

-

-

[24] (USA)

17.4% (149)

-

-

-

-

-

[52] (USA)

25.2% (131)

-

7.6% (662)

-

-

-

[53] (UK)

19.1% (235)

-

-

-

-

-

[32] (USA/Can/UK)

12.8% (266)

7.9% (496)

8.5% (142)

1.6% (313)

9.8% (123)

2.0% (250)

[35] (USA; outcomes 1998–1999)

-

4.0% (402)

-

2.0% (506)

-

1.5% (548)

[36] (USA; outcomes 1999–2000)

-

3.9% (795)

-

2.3% (690)

-

1.3% (972)

[39] (Canada)

-

6.0% (95)

-

1.3% (199)

-

-

[40] (The Netherlands)

-

3.4% (88)

-

0.8% (124)

-

-

Unpublished data (France)

-

7.6% (506)

-

-

-

-

[37] (USA; registry 2000–2001)

-

5.8% (482)

-

2.3% (650)

-

1.6% (936)

[54] (Spain)

-

-

10.1% (456)

-

-

-

[55] (Spain)

-

-

12.9% (827)

-

-

-

[41] (international study)

-

-

-

2.1% (285)

-

-

Weighted mean rate

18.4% (811)

5.6% (2864)

10.3% (2087)

2.0% (2767)

9.8% (123)

1.5% (2706)

  1. Values are expressed as % (n). Hospitalization rates due to respiratory syncytial virus (RSV) in children ≤ 2 years old with bronchopulmonary dysplasia (BPD)/chronic lung disease (CLD), infants at gestational age 29–32 weeks without CLD, and infants at gestational age 32–35 weeks without CLD (combined analysis). -, not studied. Adapted from Simoes [44].