Table 1 Known and potential sites of SP-D expression
Anatomical site | Organ | Cellular source |
|---|---|---|
Respiratory tract/oropharynx/nasopharynx | Lung | Alveolar type II cell, non-ciliated bronchiolar cells |
| Â | Trachea and bronchi | Submucosal glands and repiratory epithelial cells |
| Â | Lacrimal glands | Ductal epithelial cells |
| Â | Salivary gland | Ductal epithelial cells |
| Â | Eustachian tube | Squamous epithelium |
Gastrointestinal tract | Esophagus | Squamous epithelium |
| Â | Stomach | Glandular epithelial cells |
| Â | Small intestine | Mucosal epithelial cells |
| Â | Pancreas (exocrine) | Ductal epithelial cells (and islets) |
| Â | Biliary tract | Intrahepatic ductal epithelial cells |
Genitourinary tract | Prostate | Glandular epithelium |
| Â | Bladder | Transitional epithelium |
| Â | Kidney | Collecting duct epithelium |
| Â | Uterus | Endometrium/endocervical epithelium? |
| Â | Fetal membranes | ? |
Skin and soft tissue | Cutaneous squamous epithelium | Squamous epithelium |
| Â | Sweat glands | Ductal epithelium |
| Â | Sebaceous glands | Glandular epithelium |
| Â | Breast | Mammary epithelium |
| Â | Mesentery | ? |
Other | Heart | ? |
| Â | Brain | ? |
| Â | Testis | Leydig cells |
| Â | Pancreas (endocrine) | Islets |
| Â | Placenta | ? |