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Table 5 Increased SP-D accumulation or expression in animal models

From: Surfactant protein-D and pulmonary host defense

Injury or challenge

Species

Reference

Silicosis

Rat

[118]

Hyperoxia

Rat

[104]

Endotoxin (LPS)

Rat

[103]

Challenge with P. aeruginosa

Mouse

[92]

Challenge with IAV

Mouse

[62]

Challenge with Pneumocystis carinii

SCID mouse

[91]

 

Rat

[119]

Overexpression of interleukin-4

Mouse

[120]

  1. SCID, severe combined immunodeficiency.