Anti-inflammatory |
   Regulation of inflammatory response to microorganisms and |
   microbial products |
   `Neutralization' of LPS/altered presentation of LPS to host cells |
   Regulation of pulmonary oxidant metabolism |
Antimicrobial |
   Enhanced opsonization and killing of some organisms |
   Decreased internalization of some intracellular pathogens |
   Enhanced microbial agglutination with enhanced physical or |
   cellular clearance |
   Enhanced inflammatory response to SP-D/microbial complexes |
   Altered microbial growth |
Immunomodulatory |
   Decreased proliferative response of lymphocytes to various |
   mitogens |
   Altered presentation of antigens to specifically sensitized cells |
Proinflammatory/repair |
   Enhanced directed migration or airspace retention of phagocytes |
   Altered macrophage production of metalloproteinases |
Surfactant homeostasis |
   Altered spatial organization of PI-enriched sub-fractions of |
   surfactant lipid |
   Normal cellular uptake and metabolism of surfactant lipid |