From: Airway wall thickness is increased in COPD patients with bronchodilator responsiveness
BDR-(10%) | BDR + (10%) | BDR-(15%) | BDR + (15%) | BDR-(ATS) | BDR + (ATS) | ||||
---|---|---|---|---|---|---|---|---|---|
n = 2355 | n = 1306 | p | n = 2863 | n = 798 | p | n = 2385 | n = 1276 | p | |
%emphysema | 11.36 ± 12.34 | 12.22 ± 11.96 | .042 | 11.43 ± 12.23 | 12.53 ± 12.12 | .024 | 11.78 ± 12.77 | 11.45 ± 11.96 | .431 |
%gas trapping | 33.96 ± 20.93 | 39.04 ± 20.22 | <.0001 | 34.46 ± 20.85 | 40.48 ± 20.00 | <.0001 | 34.93 ± 20.88 | 37.36 ± 20.61 | .001 |
TLC | 6.01 ± 1.43 | 6.09 ± 1.47 | .090 | 6.01 ± 1.44 | 6.11 ± 1.48 | .095 | 5.96 ± 1.44 | 6.31 ± 1.44 | .134 |
FRC | 3.78 ± 1.2 | 4.05 ± 1.24 | <.0001 | 3.80 ± 1.20 | 4.15 ± 1.25 | <.0001 | 3.87 ± 1.25 | 3.89 ± 1.10 | <.0001 |
TLC %pred, race-adjusted | 101.15 ± 16.52 | 103.65 ± 16.42 | <.0001 | 101.34 ± 16.49 | 104.56 ± 16.44 | <.0001 | 101.56 ± 16.41 | 102.94 ± 16.70 | .016 |
FRC %pred, race-adjusted | 117.90 ± 31.85 | 127.02 ± 31.12 | <.0001 | 118.62 ± 31.69 | 130.25 ± 30.95 | <.0001 | 118.86 ± 31.55 | 125.43 ± 32.10 | <.0001 |
Pi10 | 3.69 ± 0.14 | 3.73 ± 0.15 | <.0001 | 3.69 ± 0.14 | 3.74 ± 0.15 | <.0001 | 3.69 ± 0.14 | 3.72 ± 0.15 | <.0001 |
Pi15 | 5.17 ± 0.2 | 5.24 ± 0.21 | <.0001 | 5.18 ± 0.20 | 5.26 ± 0.21 | <.0001 | 5.17 ± 0.20 | 5.24 ± 0.21 | <.0001 |
Wall area %, segmental | 61.97 ± 3.15 | 63.12 ± 2.94 | <.0001 | 62.08 ± 3.12 | 63.45 ± 2.89 | <.0001 | 62.07 ± 3.14 | 62.97 ± 3.00 | <.0001 |