Skip to main content

Table 1 Characteristics of patients with asthma

From: Small airway dysfunction is associated to excessive bronchoconstriction in asthmatic patients

 

All patients (No. 63)

Patients with R5-R20 ≤ 0.03 kPa s l−1(No. 33)

Patients with R5-R20 > 0.03 kPa s l−1(No. 30)

Age (years)

42 ± 14

38 ± 12

45 ± 15*

Sex (F/M)

36/27

13/20

23/7**

BMI (kg/m2)

24 ± 3

23 ± 2

25 ± 3

Atopy (Y/N)

52/11

31/2

21/9*

Smoking (Y/N)

12/51

9/24

4/26

ICS use (Y/N)

29/34

14/19

15/15

ICS dose (μg/day)#

701 ± 540

779 ± 598

628 ± 490

ACT > 20/ACT ≤ 19

49/14

29/4

20/10*

FEV1 (% of pred)

92 ± 14

94 ± 13

90 ± 15

FVC (% of pred)

99 ± 13

102 ± 12

97 ± 13

FEV1/SVC (%)

75 ± 8

75 ± 6

75 ± 9

FEF25–75 (% pred)

76 ± 25

77 ± 21

74 ± 29

R5-R20 (kPa s l−1)

0.057 ± 0.072

0.011 ± 0.014

0.108 ± 0.076**

X5 (kPa s l-1)

−0.134 ± 0.07

−0.098 ± 0.02

−0.172 ± 0.09**

PD20 (μg)

181 (132–249)

207 (134–322)

156 (96–254)

DRS (%/μg)

0.103 (0.074-0.143)

0.086 (0.054-0.135)

0.125 (0.076-0.205)

∆FVC%

13.6 ± 5.1

11.5 ± 4.8

15.8 ± 4.6**

  1. Values are expressed as mean ± SD, ratio or geometric mean (Confidence Intervals).
  2. #only in patients using ICS; *p < 0.05; **p < 0.01.