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Table 1 Results of chest radiographic stages, serum angiotensin-converting enzyme (sACE), lung function testing, and organ involvement in patients with newly diagnosed pulmonary sarcoidosis

From: Disposal of iNKT cell deficiency and an increase in expression of SLAM signaling factors characterizes sarcoidosis remission: a 4-year longitudinal study

 

Sarcoidosis

(N = 29)

Chest radiographic stage*

 

Stage I, n (%)

8 (28)

Stage II, n (%)

19 (66)

Stage III, n (%)

2 (7)

Lung function

 

% predicted FEV1

92 (43-114)

% FVC

94 (51-118)

% DLCO

92 (46-122)

sACE (ÎĽkat/L) **

1.0 (0.1-4.4)

Organ involved †

 

Lung involvement, n (%)

29 (100)

Multisystem, n (%)

16 (55)

Erythema nodosum, n (%)

5 (17)

(Löfgren syndrome, n (%))

5 (17)†

Skin, n (%)

6 (21)

Liver, n (%)

3 (10)

Lymphatic glands, n (%)

2 (6)

Parotid glands and spleen, n (%)

1 (3)

  1. Lung function and sACE data are presented as medians with the range.
  2. *Standard radiographic staging consists of five stages: Stage 0 = normal, Stage I = bilateral hilar lymphadenopy, Stage II = BHL and parenchymal infiltration, Stage III = radioparenchymal infiltration without BHL, and Stage IV = irreversible fibrosis with loss of lung volume.
  3. **sACE was determined by the kinetic method. Our normal values for sACE are 0.33-1.17 ÎĽkat/l. Sixteen (52%) patients had higher-than-normal concentrations of sACE.
  4. †All patients with erythema nodosum included those fulfilling the criteria of Löfgren syndrome (plus bilateral hilar adenopathy and arthralgia).
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Respiratory Research

ISSN: 1465-993X

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