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Table 2 Bronchoalveolar lavage fluid (BALF) cell counts and T lymphocytes, B lymphocytes, NK, and NKT-like cells in BALF from patients with sarcoidosis sampled upon diagnosis and control subjects

From: Disposal of iNKT cell deficiency and an increase in expression of SLAM signaling factors characterizes sarcoidosis remission: a 4-year longitudinal study

BALF cell counts

Sarcoidosis(N = 29)

Controls(N = 9)

pvalue

Total cells (×105 cells/ml)

1.2 (0.5-3.2)

1.00 (0.4-2.2)

n.s.

Neutrophils (%)

3 (1-6)

2 (1-22)

n.s.

Eosinophils (%)

1 (1-4)

1 (1-2)

n.s.

Macrophages (%)

68 (24-93)

87 (69-95)

0.003

Lymphocytes (%)

29 (6-76)

9 (3-14)

0.0005

% of lymphocytes

   

T lymphocytes (CD3+)

89 (61-97)

86 (60-97)

n.s.

T helper (CD3+CD4+)

73 (37-90)

53 (27-80)

0.008

T cytotoxic (CD3+CD8+)

11 (4-39)

23 (13-57)

0.002

B lymphocytes (CD19+)

0 (0-3)

0 (0-2)

n.s.

NK cells (CD3CD16/56+)

2 (1-32)

2 (0-4)

n.s.

nonbiased NKT cells (CD3+CD16/56+)

3.5 (1-11)

3 (2-5)

n.s.

CD4/CD8 ratio

7.29 (1-22.5)

2.2 (0.5-6.2)

0.002

  1. Data are presented as medians with the range.
  2. n.s. = non significant.