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Table 3 Mean total lung capacity measured by CT (TLC CT ) according to genotype of rs114929486 in DNAH5 (N = 4,543) *

From: DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease

 

rs114929486

GG

AG

P

All

N

4282

258

 

TLCCT, L

6.12 (1.41)

6.50 (1.52)

0.0001

COPDGene

n

2531

121

 

TLCCT, L

6.18 (1.40)

6.47 (1.47)

0.042

ECLIPSE

N

1364

99

 

TLCCT, L

6.15 (1.42)

6.84 (1.57)

1.96 × 10-5

GenKOLS

N

387

38

 

TLCCT, L

5.56 (1.30)

5.70 (1.25)

0.486

  1. Data are presented as mean (SD).
  2. *Three subjects with AA genotype (each one from each cohort) were excluded from this analysis.