Figure 3

Lung function of mice treated with CSF-1 following hyperoxia exposure. Plethysmography assessment of lung function parameters - tidal volume (A), minute volume (B), frequency (C), total cycle time (D), inspiration time (E), expiration time (F), tidal volume/bodyweight (G), minute volume/bodyweight (H), inspiratory flow rate (I) - in mice treated with CSF-1 (Hyp + CSF-1; purple line) or PBS (Hyp + PBS; blue line) following hyperoxia exposure, compared to normoxic controls (Norm; red line). n = 6-14 mice/treatment/time point. Data were analysed using two-way ANOVAs and Bonferonni post-hoc tests. `a’ represents significant difference between Norm and Hyp + PBS, `b’ represents significant difference between Norm and Hyp + CSF-1, `c’ represents significant difference between Hyp + PBS and Hyp + CSF-1. *p < 0.05, **p < 0.01, ***p < 0.001.