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Table 3 Morphometric analysis of lungs from mice administered CSF-1 during concurrent hyperoxia exposure

From: The effect of CSF-1 administration on lung maturation in a mouse model of neonatal hyperoxia exposure

  

Normoxia

Hyp + PBS

Hyp + CSF-1

P5

% Tissue

34.92 ± 1.83

28.31 ± 1.83

32.15 ± 1.74

 

% Airspace

65.08 ± 1.83

71.69 ± 1.83

67.85 ± 1.74

 

MLI

113.00 ± 3.22

121.70 ± 7.97

116.40 ± 3.45

P35

% Tissue

36.97 ± 1.29

38.48 ± 2.01

36.92 ± 0.88

 

% Airspace

63.03 ± 1.29

61.52 ± 2.01

63.08 ± 0.88

 

MLI

64.99 ± 1.78

72.66 ± 1.22 a*

75.27 ± 2.79 b**

  1. Morphometric estimation of percentage tissue, percentage airspace and mean linear intercept at P5 at the cessation of treatment (n = 4-5/group), and at P35 (n = 6-7/group). Data were analysed by one-way ANOVA and Tukey’s post-hoc test. `a’ represents significant difference between Norm and Hyp + PBS, `b’ represents significant difference between Norm and Hyp + CSF-1. *p < 0.05, **p < 0.01.