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Table 2 Airway and systemic inflammation in colonised* and non-colonised samples

From: Inflammatory thresholds and the species-specific effects of colonising bacteria in stable chronic obstructive pulmonary disease

 

Non-colonised samples

Colonised samples

p-value

 

n = 119

n = 64

Median (IQR) CXCL8 (ng.ml -1 )

83 (24-182)

162 (71-309)

<0.001

Median (IQR) IL-1β (ng.ml -1 )

0.6 (0.2-1.9)

1.4 (0.7-5.9)

<0.001

Median (IQR) MPO (μg.ml -1 )

17.1 (7.6-30.6)

29.5 (16.2-40.9)

<0.001

Median (IQR) CRP (mg.l -1 )

2.0 (1.0-8.0)

2.0 (1.0-5.0)

0.261

Median (IQR) Fibrinogen (g.l -1 )

3.5 (3.2-4.1)

3.8 (3.3-4.4)

0.049

  1. *Bronchial colonisation defined as sputum sample positive Haemophilus influenzae (HI), Streptococcus pneumoniae (SP) and/or Moraxella catarrhalis (MC) using quantitative polymerase chain reaction (qPCR).