Figure 7
From: Inhibition of AMPK expression in skeletal muscle by systemic inflammation in COPD rats
AICAR and Resveratrol increased the expression of muscle SirT1 in muscle tissue in COPD model rats. Muscle SirT1 (Control: n = 6; 0.55 ± 0.04; COPD/saline: n = 6, 0.44 ± 0.03; COPD/AICAR, n = 6, 0.73 ± 0.02; COPD/Resveratrol, n = 6, 0.73 ± 0.03). n.s. F 1, 11 = 5.0, p = 0.051 comparing the control group to COPD/saline group. ***F 2, 17 = 48.69, p < 0.001 comparing the COPD/saline group to COPD/AICAR and COPD/resveratrol group respectively. n.s. (not significant).