Table 1 Signaling receptors responding to secreted or cleaved factors that are expressed on human tracheal basal cells
Marker | Receptor | Ligand | Mean frequency of positive cells |
|---|---|---|---|
CD136 | MST1R/RON | MSP | 99.8 |
CD95 | FAS | TNFSF6/FASLG | 99.5 |
CD222 | IGF2R | IGF2 | 99.0 |
CD221 | IGF1R | IGF1 | 98.2 |
CD340 | ERBB2 | EGF | 97.7 |
CD119 | IFNGR1 | IFNg | 97.1 |
EGFR | EGFR | EGF | 95.6 |
CD261 | TNFRSF10A | TNFSF10/TRAIL | 87.1 |
CD262 | TNFRSF10B | TNFSF10/TRAIL | 86.2 |
CD264 | TNFRSF10D | TNF | 66.4 |
CD271 | NGFR | NGF, BDNF, NT-3, NT-4 | 53.9 |
CD130 | IL6ST (coreceptor for IL6R, LIFR) | IL6, LIF | 43.6 |
CDW218a | IL18R1 | IL18 | 22.5 |
CD181 | CXCR1 | IL8 | 19.2 |
CD132 | IL2RG (coreceptor for IL7RA, IL9R) | IL17A, IL9 | 18.7 |
CD295 | LEPR | Leptin | 10.0 |
CD117 | CKIT | SCF | 3.79 |
CDW198 | CCR8 | TARC, MIPb | 2.23 |
CD193 | CCR3 | CCL11, CCL26, CCL7, CCL13, CCL5 | 1.84 |
CD126 | IL6R | IL6 | 1.49 |
CD266 | TNFRSF12A | TNFSF12 | 1.08 |
CD304 | NRP1 | SEM3A, VEGF-165, PLGF-2 | 1.01 |
CD195 | CCR5 | MCP2, MIP-1a, MIP-1b, CCL5 | 0.656 |
CD182 | CXCR2 | IL8 | 0.643 |
CD218b | IL18RAP | IL18 | 0.557 |
CD120b | TNFRSF1B | TNFSF2/TNFa, TNFSF1/LTA | 0.537 |
PAC1 | ADCYAP1R1 | PACAP-27, PACAP-38 | 0.517 |
CD129 | IL9R | IL9 | 0.459 |
CD184 | CXCR4 | CXCL12 | 0.447 |
CD120a | TNFRSF1A | TNFSF2/TNFa, TNFSF1/LTA | 0.318 |
CD217 | IL17RA | IL17A | 0.232 |
CD309 | KDR/VEGFR2 | VEGF | 0.196 |
CD118 | LIFR | LIF | 0.169 |