Figure 3

Concentrations of inflammatory mediators in upper airway lavages of mice chronically exposed to CS and colonized with NTHi or S. pneumoniae . Mice were exposed to CS or air for 3 months and intranasally inoculated with NTHi or S. pneumoniae (S.p.). Concentrations of KC (A), RANTES (B), and IL-6 (C) were measured in upper airway lavages of mice by CBA 24 hours (NTHi) and 4 days (S.p.) postinoculation. Data are shown as mean ± SEM. Bars indicate significant differences of *p < 0.05 and **p < 0.01, n ≥ 5 per group.