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Figure 3 | Respiratory Research

Figure 3

From: Megakaryoblastic leukemia-1 is required for the development of bleomycin-induced pulmonary fibrosis

Figure 3

The early inflammatory response to bleomycin does not differ between MKL1 (+,+) and MKL1 (−,-) mice. A. Total BAL cell counts obtained 3 days following intratracheal saline or bleomycin treatment in MKL1 (+,+) and MKL1 (−,-) mice. B. Absolute neutrophil counts from the day 3 BALs obtained in Figure 3 A. C. Modified Ashcroft scores from trichrome-stained MKL1 (+,+) and MKL1 (−,-) mouse lungs done 3 days after bleomycin treatment. D. BAL differential cell counts of the same day 3 groups as in Figure 3 A, depicting the percentage of neutrophils, macrophages, lymphocytes and eosinophils counted following saline and bleomycin treatment in MKL1 (+,+) and MKL1 (−,-) mice. E. Total BAL cell counts obtained 7 days following intratracheal saline or bleomycin treatment in MKL1 (+,+) and MKL1 (−,-) mice. F. Absolute neutrophil counts from the day 7 BALs obtained in Figure 3 E. G. Modified Ashcroft scores from trichrome-stained MKL1 (+,+) and MKL1 (−,-) mouse lungs done 7 days after bleomycin treatment. H. BAL differential cell counts of the same day 7 groups as in Figure 3 E, depicting the percent of neutrophils, macrophages, lymphocytes and eosinophils counted following saline and bleomycin treatment in MKL1 (+,+) and MKL1 (−,-) mice. One-way ANOVA (p < 0.05) was performed to test for statistical significance.

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