Table 2 Characteristics of the SNPs genotype frequencies (GF) and their associations with COPD risk in different group of subjects

HHIP

rs11100865

145870597

G → A

GG

0.239/0.284

reference

0.229/0.299

reference

0.213/0.282

reference

AG

0.448/0.498

0.166

1.287(0.900-1.841)

0.477/0.492

0.262

1.266(0.838-1.912)

0.525/0.504

0.301

1.382(0.749-2.551)

AA

0.313/0.218

0.007

1.715(1.162-2.532)

0.294/0.209

0.001

1.925(1.214-2.687)

0.263/0.214

0.17

1.637(0.809-3.313)

rs12504628

145655774

T → C

TT

0.500/0.506

reference

0.519/0.497

reference

0.550/0.493

reference

CT

0.351/0.421

0.383

0.829(0.543-1.264)

0.360/0.430

0.265

0.815(0.569-1.168)

0.375/0.430

0.477

0.829(0.493-1.392)

CC

0.149/0.073

0.018

2.114(1.136-3.935)

0.121/0.072

0.116

1.597(0.891-2.863)

0.075/0.074

0.81

0.890(0.436-2.291)

rs13118928

145705839

A → G

AA

0.470/0.457

reference

0.495/0.441

reference

0.538/0.446

reference

AG

0.373/0.459

0.298

0.801(0.527-1.217)

0.379/0.474

0.069

0.718(0.502-1.026)

0.389/0.475

0.148

0.685(0.410-1.143)

GG

0.158/0.083

0.048

1.839(1.005-3.365)

0.126/0.085

0.317

1.334(0.758-2.348)

0.075/0.079

0.629

0.792(0.309-2.035)

rs7654947

145845180

T → C

TT

0.321/0.417

reference

0.327/0.433

reference

0.338/0.441

reference

CT

0.440/0.402

0.112

1.433(0.920-2.235)

0.453/0.387

0.023

1.552(1.062-2.267)

0.475/0.372

0.042

1.750(1.020-3.001)

CC

0.239/0.182

0.027

1.820(1.070-3.096)

0.220/0.180

0.004

1.882(1.192-2.816)

0.188/0.166

0.039

1.842(1.201-2.568)

FAM13A

rs7671167

90103002

T → C

TT

0.313/0.252

reference

0.322/0.235

reference

0.338/0.224

reference

CT

0.463/0.442

0.43

0.832(0.527-1.314)

0.463/0.438

0.222

0.779(0.522-1.163)

0.463/0.443

0.426

0.791(0.443-1.411)

CC

0.224/0.306

0.046

0.582(0.342-0.990)

0.215/0.327

0.002

0.480(0.303-0.762)

0.200/0.335

0.027

0.458(0.229-0.915)