Skip to main content
Fig. 2 | Respiratory Research

Fig. 2

From: A flavanone from Baccharis retusa (Asteraceae) prevents elastase-induced emphysema in mice by regulating NF-κB, oxidative stress and metalloproteinases

Fig. 2

Mean alveolar diameter (Lm) and pulmonary remodeling. The data are presented as the mean and SE for the four groups. The Lm a, which correlates with alveolar destruction, was increased in the ELA+Ve group c compared with the control group b. Sakuranetin treatment attenuated this response in ELA+SK animals d. Pulmonary remodeling was characterized by collagen e and elastic f fiber content in the alveolar septum. There was increased deposition of collagen and elastic fibers in the alveolar septum in the animals that received elastase (collagen h and elastic k fibers). Sakuranetin treatment (ELA+SK) attenuated this response (collagen i and elastic l fibers) and generated values that were similar to those in the control group g represent collagen and j elastic fibers). Collagen and elastic fibers are indicated by arrows. *p < 0.001 compared with the SAL+Ve group; **p < 0.001 (A) and **p < 0.05 (E) compared with the ELA+Ve group

Back to article page

Respiratory Research

ISSN: 1465-993X

Contact us