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Table 6 Propensity score matching

From: Acute exacerbations of COPD are associated with significant activation of matrix metalloproteinase 9 irrespectively of airway obstruction, emphysema and infection

Variable

Stable COPD n = 35

AE-COPD n = 35

P-Value

Age

69.2 (6.44)

69.5 (9.80)

0.863

Sex

0.37 (0.49)

0.43 (0.50)

0.632

Packs per year

50.6 (23.1)

47.9 (36.1)

0.715

FEV1 % predicted

50.7 (21.6)

48.6 (16.3)

0.653

RV % predicted

153 (46.5)

160 (45.9)

0.527

DLCO % predicted

46.8 (19.8)

46.2 (16.7)

0.885

Bacteriology

  

1.000

negative

19 (54.3 %)

19 (54.3 %)

 

positive

16 (45.7 %)

16 (45.7 %)

 

Virology

  

0.511

negative

31 (88.6 %)

28 (80.0 %)

 

positive

4 (11.4 %)

7 (20.0 %)

 

activation of MMPa

1.28 (0.97)

0.56 (0.56)

0.018

  1. AE acute exacerbation, FEV1 forced expiratory volume in one second, RV residual volume, DLCO diffusion capacity of the lung for carbon monoxide
  2. aExpressed as the ratio of proMMP-9/MMP-9