Fig. 3From: Increased ectodomain shedding of cell adhesion molecule 1 as a cause of type II alveolar epithelial cell apoptosis in patients with idiopathic interstitial pneumoniaImmunohistochemical analysis of CADM1 in IIP lungs. IIP lung sections were stained immunohistochemically with an anti-CADM1 antibody and counterstained with hematoxylin. Representative results for f-NSIP and UIP are shown. Boxed areas are enlarged to depict different subcellular localizations of CADM1 in AECIIs that are lining the alveolar lumen (a, c and e), detaching (d and e), or detached (b) from the alveolar wall. Bar = 50 μm. Results of the other subtypes are shown in Additional file 4: Figure S3Back to article page