Skip to main content
Fig. 4 | Respiratory Research

Fig. 4

From: Asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) longitudinal profiling study

Fig. 4

Correlation matrix across clinical and biomarker measures. Spearman correlation coefficients are reported for the pairing of variables indicated on the y-axis vs. x-axis, using values from asthma subjects only (healthy controls excluded) from baseline visit, for blood differentials from the screening visit, and for PC20 from either the screening or baseline visit. Color scale ranges from blue (r = −1) to white (r = 0) to red (r = 1). P- values <0.05 were considered to be statistically significant. Correlations among variables were tested using Spearman correlation tests that do not require assumptions of normality and linearity. Because of the large number of pair-wise comparisons, a significance threshold of p < 0.0004 was established by the Bonferroni adjustment method to maintain a family-wise error rate <0.05 for the 136 pair-wise comparisons of 16 variables

Back to article page