| Pre-BD FEV1 ≥ 80 % predicted normal | Pre-BD FEV1 ≥ 60- < 80 % predicted normal | Pre-BD FEV1 ≥ 50- < 60 % predicted normal | Pre-BD FEV1 < 50 % predicted normal |
---|---|---|---|---|
Controller medication | ||||
None | Eligible for mild asthma cohort | Ineligible | Ineligible | Ineligible |
Low to medium ICS alone or in combination with other controllers except chronic oral corticosteroids and omalizumab | Ineligible | Eligible for moderate asthma cohort | Ineligible | Ineligible |
High dose ICS alone or in combination with other controllers including chronic oral corticosteroids and omalizumab | Ineligible | Eligible for severe asthma cohort | Eligible for severe asthma cohort | Ineligible |