Fig. 1
From: Anti-inflammatory potential of PI3Kδ and JAK inhibitors in asthma patients
Effects of PIK-294 and tofacinib on cytokine release in BAL cells from asthma patients (n = 12) and healthy subjects (n = 11). BAL cells were treated with varying concentrations of PIK-294 or tofacitinib for 1 h before being stimulated with antibodies against CD3 and CD28 to induce a TCR-specific response. Cytokines were measured by ELISA. Data is presented as mean % inhibition (+/−SEM) of maximum cytokine release