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Table 1 Clinical characteristics of patients

From: Extracellular ATP is involved in dsRNA-induced MUC5AC production via P2Y2R in human airway epithelium

 

Healthy subjects (n = 5)

COPD (n = 5)

Sex (Male/Female)

1/4

5/0

Age (years)

69.5 ± 6.06

70.6 ± 3.84

Ex-smoker

1

5

smoking history (pack-year)

8.0 ± 17.9

76.7 ± 73.7*

FVC (L)

2.82 ± 0.24

3.30 ± 0.38*

FVC % predicted

115 ± 12.3

96.0 ± 7.89*

FEV1 (L)

2.18 ± 0.15

2.14 ± 0.50

FEV1 % predicted

113 ± 19.2

74.3 ± 17.0*

FEV1/FVC (%)

77.5 ± 9.54

64.0 ± 10.2

DLCO/VA % predicted

102 ± 10.5

86.2 ± 8.62*

  1. COPD chronic obstructive pulmonary disease; pack-year: 1 year smoking 20 cigarettes-day; FVC forced vital capacity; FEV1 forced expiratory volume in one second; DLCO diffusing capacity of the lung for carbon monoxide; VA alveolar volume. Values are mean ± SE. *p < 0.05 compared to healthy subjects