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Fig. 3 | Respiratory Research

Fig. 3

From: High levels of biomarkers of collagen remodeling are associated with increased mortality in COPD – results from the ECLIPSE study

Fig. 3

Cox proportional hazards ratios for death. Hazard ratios (HR) for death are shown per one standard deviation increase in biomarker (a + b) and for subjects in the upper vs. lower quartile (c + d). Cox proportional HR with 95 % confidence intervals are shown for crude analyses (a + c) and analyses adjusted for age, BODE, and previous exacerbations (b + d). All biomarkers, with the exception of BGM, ELM7, and EL-NE, were significantly related to mortality outcome in both crude and adjusted analyses. Statistical significant hazard ratios are indicated as *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001

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