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Fig. 3 | Respiratory Research

Fig. 3

From: T cells suppress memory-dependent rapid mucous cell metaplasia in mouse airways

Fig. 3

Elevated expression of TLR4, EGFR and phosphorylated-ERK1/2 (pERK) in LPS-pretreated F344/N rats following the second LPS challenge. a Quantification of the AECs with apically localized TLR4 and EGFR in S/0, S/100, L/0 and L/100 rats. Representative micrographs of axial airways from S/0, S/100, L0 and L/100 rats with airways stained with DAPI (blue) nuclei, TLR4 (red), EGFR (green) and a merged image. b Quantification of the AECs with nuclear phosphorylated-ERK1/2 (p-ERK) in S/0, S/100, L/0 and L/100 rats. Representative micrographs of axial airways stained for pERK (green) and DAPI-stained (blue) nuclei are shown. Error bar indicates mean ± SEM (n = 5–6 per group). * P < 0.05, ** P < 0.01 compared to S/0 unless otherwise indicated

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