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Table 3 Comparing serum biomarker levels 2005 among survivors and subjects deceased during the observation time, in non-COPD and COPD respectively

From: Proteolytic biomarkers are related to prognosis in COPD- report from a population-based cohort

Biomarkers

non–COPD

P

COPD

P

Participating

n = 860

Deceased

n = 88

Participating

n = 513

Deceased

n = 81

 

Median (IQR)

Median (IQR)

 

Median (IQR)

Median (IQR)

 

MMP-9 (ng/ml)

501 (346–605)

535 (428–628)

0.026

514 (210–641)

607 (493–681)

< 0.001

TIMP-1 (ng/ml)

311 (224–521)

327 (250–381)

0.670

300 (222–479)

311 (260–366)

0.839

MMP-9/TIMP-1 ratio

1.34 (0.81–2.09)

1.71 (1.19–2.16)

0.001

1.38 (0.76–2.29)

1.86 (1.52–2.34)

< 0.001

  1. IQR Inter quartile range. Significant p-values in bold