Skip to main content
Fig. 2 | Respiratory Research

Fig. 2

From: Recurrent inhibition of mitochondrial complex III induces chronic pulmonary vasoconstriction and glycolytic switch in the rat lung

Fig. 2

Antimycin A induced pulmonary injury on Day 12. Photomicrographs of whole lob section of lung tissue from control (a) and Antimycin A 12 days challenged lungs (b). Lung wet to dry ratio indicates significantly increased edema at day 12 (c). Normal perivascular structure in control animal (d) and marked (e) and severe (f) pulmonary perivascular edema in AA-treated rats at Day 12. Although the total wet lung weight normalized by body weight shows an increase right after AA injection, this acute lung edema was not significant (g). However, by day 12 the difference in the lung weight as a measure of pulmonary edema became significant compared to Control group (g) H&E staining. Photomicrographs are representative of 5 lung preparations per experimental group. For lung edema evaluation the data are mean ± SEM, N = 4–6 per group. *P < 0.05 vs. Control using unpaired t-test

Back to article page