Table 2 Cut-off values and diagnostic accuracy measures of AGEs, sRAGE and AGEs/sRAGE ratio
From: Serum AGE/RAGEs as potential biomarker in idiopathic pulmonary fibrosis
|  | IPF – fNSIP | cHP – fNSIP | ||||
|---|---|---|---|---|---|---|
Indicators | AGE | sRAGE | Ratio | AGE | sRAGE | Ratio |
Cut-off value | 19.25 μg/ml | 782.59 pg/ml | 25.65 ‰ | 20.92 μg/ml | 529.57 pg/ml | 24.87 ‰ |
Sensitivity (%) | 69.77 | 89.66 | 100.00 | 73.33 | 85.71 | 75.00 |
Specificity (%) | 85.00 | 64.71 | 94.12 | 95.00 | 82.35 | 88.24 |
Accuracy (%) | 74.60 | 84.00 | 98.28 | 85.71 | 83.87 | 81.82 |
LR+ | 4.65 | 2.54 | 17.00 | 14.67 | 4.86 | 6.38 |
J | 0.55 | 0.54 | 0.94 | 0.68 | 0.68 | 0.63 |