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Table 1 Patient demographic data, lung function parameters and blood gas analysis (room air breathing) at baseline

From: Nebulization versus standard application for topical anaesthesia during flexible bronchoscopy under moderate sedation – a randomized controlled trial

 

Lidocaine

Difference between means (95% CI)

p-value

Syringe

(n = 30)

Nebulizer (n = 30)

Male, n (%)

18 (60)

21 (63.6)

–

0.8001*

Age, years

64.47 ± 11.56

67.9 ± 9.08

−3.43 ± 2.68 (− 8.81, 1.94)

0.2059#

Body weight, kg

79.33 ± 16.5

86.64 ± 15.81

−7.31 ± 4.17 (− 15.66, 1.05)

0.0852#

Smoking history, pack years

5 (0–30)

5 (0–30)

–

0.7064§

FEV1, % predicted

77.5 ± 21.1

74.18 ± 21.24

3.32 ± 5.66 (−8.03, 14.68)

0.5600#

PaO2, mmHg

69.29 ± 18.6

66.56 ± 12.99

2.73 ± 4.14 (−5.56, 11.02)

0.5124#

PaCO2, mmHg

38.1 ± 8.84

36.36 ± 3.64

1.74 ± 1.75 (−1.75, 5.23)

0.3288#

ASA 1/2 or 3/4, n (%)

16 (53.3); 14 (46.7)

16 (53.3)

–

> 0.9999*

  1. Data are presented as mean ± standard deviation, median (interquartile range) or number of patients (%)
  2. *Fisher’s exact test. #Unpaired t-test. §Mann Whitney test
  3. ASA, American Society of Anesthesiologists; CI, confidence interval; FEV1, forced expiratory volume in 1 s; PaCO2, arterial partial pressure of carbon dioxide; PaO2, arterial partial pressure of oxygen
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Respiratory Research

ISSN: 1465-993X

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