Fig. 4

Changes of chest CT before and after treatment, a CT contrast of complete absorption of the lesion after 6 months of treatment. After 6 months of treatment, the lesion was completely absorbed. b CT contrast of apparent absorption of the lesion after treatment. The re-examination of chest CT showed that the lesion was obviously absorbed after 6 months of treatment. After 6 months of treatment, the patient stopped taking medicine and were followed up for additional 6 months (12 months); further slow absorption of the lesion was shown on chest CT. c CT contrast of partial absorption of the lesion after treatment. The re-examination of chest CT showed slight absorption after 6 months of treatment. The patient stopped taking medicine after 6 months of treatment. Follow-up of chest CT at 12 months showed that the lesion was stable. d Slight absorption of the lesion after 6 months of treatment and slight increase of the lesion after withdrawal for 6 months. The re-examination of chest CT showed similar lesions after 6 months of treatment. After the completion of 6 months of treatment, the patient stopped taking medicine, and the follow-up chest CT showed slightly increased lesions at 12 months. e The treatment of GM-CSF 75μg /d for 1 month showed poor efficacy, and the lesion was absorbed after the dose was increased to 150μg/d. The patient received GM-CSF 75μg /d treatment for 1 month, and the re-examination of chest CT showed no absorption, so the amount was increased to 150μg/d for 1 month, and the re-examination of chest CT showed absorption