From: Serum urate and lung cancer: a cohort study and Mendelian randomization using UK Biobank
Coefficient per 100 µmol serum urate* | p value | Coefficient per 100 µmol serum urate* | p value | Incidence change per 10,000 PYs | |
---|---|---|---|---|---|
FEV1 (ml) | IRR lung cancer | ||||
Overall | − 10.5 (− 23 to 2.1) | 0.10 | 0.88 (0.68–1.14) | 0.33 | − 0.98 (− 2.95 to 1.00) |
Never | − 12.3 (− 28.5 to 3.9) | 0.14 | 0.88 (0.42–1.85) | 0.74 | − 0.25 (− 1.76 to 1.26) |
Former | − 12.0 (− 32.9 to 8.9) | 0.26 | 0.86 (0.59–1.26) | 0.43 | − 1.36 (− 4.75 to 2.03) |
Current | 11.0 (− 32.9 to 55.0) | 0.62 | 0.91 (0.61–1.34) | 0.62 | − 3.40 (− 17.01 to 10.21) |
Overall regular | − 5.0 (− 28.9 to 18.8) | 0.68 | 0.88 (0.66–1.18) | 0.40 | − 2.43 (− 8.09 to 3.24) |
Light former | − 14.3 (− 50.7 to 22.2) | 0.44 | 1.60 (0.69–3.70) | 0.27 | 3.63 (− 2.83 to 10.08) |
Heavy former | − 17.6 (− 54.0 to 18.8) | 0.34 | 0.68 (0.42–1.10) | 0.12 | − 6.11 (− 13.73 to 1.52) |
Current light | 15.9 (− 43.5 to 75.3) | 0.60 | 1.00 (0.54–1.86) | 1.00 | 0.05 (− 23.32 to 23.43) |
Current heavy | 40.9 (− 37.7 to 119.4) | 0.31 | 0.56 (0.31–1.00) | 0.05 | − 39.10 (− 78.36 to 0.16) |